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PATENTS

 

Treating malignant tumors with high field strength electroporation of plasmids encoding IL-12
Inventors:  Richard Heller, Melinda Lee Lucas
Patent No.: 8,026,223
Patent issued: September 27, 2011
 
Molecular delivery to cells using aspirin-related compounds
Inventors:  Mark Jaroszeski, Jennifer Langham, Richard Heller, Richard Gilbert
Patent No.: 8,017,368
Patent issued: September 13, 2011
 
Electroporation system and method for facilitating entry of molecules into cells in vivo
Inventors:  Richard Heller, Mark Jaroszeski, Richard Gilbert
Patent No.: 7,879,610
Patent issued: February 1, 2011
 
Electroporation device
Inventors:  Andrew Hoff, Richard Gilbert, Richard Heller, Mark Jaroszeski
Patent No.: 7,781,195
Patent issued: August 3, 2010
 
Electromanipulation device and method
Inventors:  Richard Heller, Mark Jaroszeski, Richard Gilbert
Patent No.: 7,769,440
Patent issued: August 24, 2010
 
Method of using electric fields to facilitate the entry of molecules into cells in vivo
Inventors:  Mark Jaroszeski, Richard Gilbert, Richard Heller
Patent No.: 7,713,740
Patent issued: May 11, 2010

 

Electroporation and electrophoresis system and method for achieving molecular penetration into cells in vivo

Inventors:         Richard Heller, Richard Gilbert, Mark J. Jaroszeski, Loree C. Heller, Melinda L. Lucas

Patent No.:       7,668,592

Patent Issued:   February 23, 2010

                             

Method and Device for Creating a Micro Plasma Jet

Inventors:         Abdel Aleam H. Mohamed, Karl H. Schoenbach, Juergen F. Kolb

Patent No.        7,752,998

Patent Issued:   August 11, 2009

 

Activation of Calcium-Mediated Cell Functions in Cells and Tissues, Including Aggregation of Human Platelets, by Nanosecond Pulsed Electric Fields

Inventors:        Peter F. Blackmore, Stephen J. Beebe, E. Stephen Buescher, Karl H. Schoenbach

Patent No.        7,565,201

Patent Issued:   July 21, 2009

 

Device and Method for Gas Treatment Using Pulsed Corona Discharge

Inventors:         M.A. Malik and K.H. Schoenbach

Patent No.        7,298,092

Patent Issued:   November 20, 2007

 

Nonpenetrating electroporation device

Inventors:         Mark J. Jaroszeski, Richard Gilbert, Richard Heller

Patent No.:       6,937,890

Patent Issued:   August 30, 2005

 

Corona ion generating method and apparatus for the manipulation of molecules and biological cells

Inventors:         Drew Hoff, Mark J. Jaroszeski, Richard Gilbert, Richard Heller

Patent No.:       6,929,949

Patent Issued:   August 16, 2005

 

Electroporation device

Inventors:         Richard Heller, Richard Gilbert, Mark J. Jaroszeski

Patent No.:       6,778,853

Patent Issued:   August 17, 2004

 

Electroporation and electrophoresis system and method for achieving molecular penetration into cells in vivo

Inventors:         Richard Heller, Richard Gilbert, Mark J. Jaroszeski, Loree C. Heller, Melinda L. Lucas

Patent No.:       6,714,816

Patent Issued:   March 30, 2004

 

Monochromatic Vacuum Ultraviolet Light Source for Photolithography Applications Based on a High Pressure Microhollow Cathode Discharge

Inventors:         K. Becker, P. Kurunci, K.H. Schoenbach

Patent No.        6,703,771

Patent Issued:   March 9, 2004

 

Method of treatment using electroporation mediated delivery of drugs and genes

Inventors:         S.B. Dev, Gunter A. Hofmann, Mark J. Jaroszeski, Richard Gilbert, Richard Heller

Patent No.:       6,569,149

Patent Issued:   May 27, 2003

 

Discharge Device Having Cathode with Micro Hollow Array

Inventors:         K. H. Schoenbach, V. Byszewski, F. Peterkin, and A. Dharamsi

Divisional

Patent No:        6,518,692

Patent Issued:   February 11, 2003

 

Method of treatment using electroporation mediated delivery of drugs and genes

Inventors:         S.B. Dev, Gunter A. Hofmann, Richard Gilbert, Yasuhiko Hayakawa, Richard Heller, Mark J. Jaroszeski

Patent No.:       6,451,002

Patent Issued:   September 17, 2002

 

Direct Current High-Pressure Glow Discharges

Inventors:          Robert P. Stark and Karl H. Schoenbach

Patent No:        6,433,480

Patent Date:      August 13, 2002

 

Needle electrode assembly for electroporation mediated delivery of genes and drugs

Inventors:         Gunter A. Hofmann, Richard Gilbert, Richard Heller, Mark J. Jaroszeski

Patent No.:       6,418,341

Patent Issued:   July 9, 2002

 

Electrofusion chamber

Inventors:         Mark J. Jaroszeski, Richard Gilbert, Richard Heller

Patent No.:       6,355,485

Patent Issued:   March 12, 2002

 

Discharge Device Having Cathode with Micro Hollow Array

Inventors:         K. H. Schoenbach, V. Byszewski, F. Peterkin, and A. Dharamsi

Divisional

Patent No:        6,346,770

Patent Issued:   February 12, 2002

 

Method and Apparatus for Intracellular Electromanipulation

Inventors:         Karl H. Schoenbach, Stephen J. Beebe, and E. Stephen Buescher

Divisional

Patent No:        6,326,177

Patent Issued:   December 4, 2001

 

 

Nonpenetrating electroporation device and method

Inventors:         Richard Gilbert, Mark J. Jaroszeski, Richard Heller

Patent No.:       6,314,316

Patent Issued:   November 6, 2001

 

Electrofusion chamber

Inventors:         Mark J. Jaroszeski, Richard Gilbert, Richard Heller

Patent No.:       6,221,665

Patent Issued:   April 24, 2001

 

Electroporation device and method

Inventors:         Richard Heller, Richard Gilbert, Mark J. Jaroszeski

Patent No.:       6,135,990

Patent Issued:   October 24, 2000

 

Discharge Device Having Cathode with Micro Hollow Array

Inventors:         K. H. Schoenbach, V. Byszewski, F. Peterkin, and A. Dharamsi

Divisional

Patent No:        5,939,829

Patent Issued:   August 17, 1999

 

Sertoli cells as transplantation facilitator for cell transplantation

Inventors:         Paul R. Sanberg, Don F. Cameron, Cesario V. Borlongan, Richard Heller

Patent No.:       5,830,460

Patent Issued:   November 3, 1998

 

Purified and isolated serotoli cell-secretory cell hybrid

Inventors:         Richard Heller, Don F. Cameron, Paul R. Sanberg, Mark J. Jaroszeski

Patent No.:       5,827,736

Patent Issued:   October 17, 1998

 

Field Controlled Plasma Discharge Printing Device

Inventors:         William C. Nunnally and Karl H. Schoenbach

Continuation in Part of U.S. Patent No.5,543,704

Patent No:        5,765,073

Patent Issued:   June 9, 1998.

 

Needle electrodes for mediated delivery of drugs and genes

Inventors:         Gunter A. Hofmann, Richard A. Gilbert, Yasuhiko Hayakawa, Richard Heller, Mark J. Jaroszeski

Patent No:        5,702,359

Patent Issued:   December 30, 1997

 

Discharge Device Having Cathode with Micro Hollow Array

Inventors:         K. H. Schoenbach, V. Byszewski, F. Peterkin, and A. Dharamsi

Patent No:        5,686,789

Patent Issued:   November 11, 1997

 

Field Controlled Plasma Discharge Device

Inventors:         Karl H. Schoenbach and William C. Nunnally

Patent No.:       5,561,348

Patent Issued:   October 1, 1996

 

Electron Beam Controlled Bulk Semiconductor Switch with Cathodoluminescent Electron Activation

Inventors:         Karl H. Schoenbach, Ralf P. Brinkmann, Vishnukumar K. Lakdawala, Glenn A. Gerdin

Continuation in part of U.S. Patent No. 4,231,248

Patent No:        4,916,303

Patent Isssued: April 10, 1990

 

 

Electron Beam Controlled Bulk Semiconductor Switch with Cathodoluminescent Electron Activation

Inventors:         Karl H. Schoenbach, Vishnukumar K. Lakdawala, Rudolf K. F. Germer, Klemens S. Schmitt

Patent No.:       4,831,248

Patent Issued:   May 16, 1989

                                   

Optically Controlled Bulk Semiconductor Switch Not Requiring Radiation to Sustain Conduction

Inventors:         Karl H. Schoenbach, Rudolf K. F. Germer, Vishnukumar K. Lakdawala, Sacharia Albin Patent No.: 4,825,061

Patent Issued:   April 25, 1989