Publications
Book
Peer Reviewed Publications
2017
F. Varghese, J.U. Neuber, F. Xie, J.M. Philpott, A.G. Pakomov, and C.W. Zemlin,
“Low-Energy Defibrillation with Nanosecond Electric Shocks”, Cardiovascular Research 113:1789-1797 (2017).
[pdf]
M. Francis, E. Breathwaite, F. Varghese, A. Bulysheva, A.M. Tichy, R.Rodriguez, R. Ogle, S. Dutta, I. Semenov, S. Chen, A. Smith, and C.W.Zemlin.
"Decellularized Placenta Hydrogel Injections Reduce Scarring in a Rat Model of Cardiac Ischemia and Support Cardiovascular and Stem Cell Cultures", Acta Biomater. 52:92-104 (2017).
[pdf]
J. M. Philpott and C. W. Zemlin.
"Neo-Arch and Descending Aortic Reconstruction Using Composite Homograft to Treat infected Arch Aneurysm and Descending Aortic Stent Graft”, J Thorac Cardiovasc Surg. 153:e73-75 (2017).
[pdf]
2016
F. Varghese, J. Burket, A. Benson, S. I. Deutsch, and C. W. Zemlin.
"Automated Analysis of Mouse Sociability”, Journal of Visual Experiments 111, pp. e52508 ff. (2016).
[pdf]
F. Xie and C.W. Zemlin.
"Effect of Twisted Fiber Anisotropy in Cardiac Tissue on Ablation with Electric Fields”, PLoS One 11, e0152262 (2016).
[pdf]
B. Hargrave, F. Varghese, N. Barabutis, J. Catravas, and C. W. Zemlin.
"Nanosecond Pulsed Platelet-Rich Plasma (nsPRP) Improves Mechanical and Electrical Cardiac Function Following Myocardial Reperfusion Injury”, Physiol Rep 4 (4), e12710 (2016).
[pdf]
2015
C. W. Zemlin, F. Varghese, M. Wellner, and A. M. Pertsov.
"Refraction of Scroll Wave Filaments and the Validity of the Geodesic Principle”, Physical Review Letters 114, 118303 (2015).
[pdf]
F. Xie, Frency Varghese, I. Semenov, A.G Pakhomov, S. Xiao, and C.W. Zemlin
“Ablation of Myocardial Tissue With Nanosecond Pulsed Electric Fields”, PLoS One 10, e0144833 (2015).
[pdf]
J. M. Philpott, C. W. Zemlin et al.
“The ABLATE Trial: Safety and Efficacy of Cox Maze-IV Using a Bipolar Radiofrequency Ablation System”, Ann Thorac Surg 100, pp. 1541-8 (2015).
[pdf]
I. Semenov, C.W. Zemlin, O.N. Pakhomova, S.Xiao, and A.G. Pakhomov
“Diffuse, non-polar electropermeabilization and reduced propidium uptake distinguish the effect of nanosecond electric pulses”, Biochim Biophys Acta 10, pp. 2118-25 (2015).
[pdf]
2014 and earlier (selected)
F. Varghese, A. M. Pertsov, and C. W. Zemlin,
“Scroll Wave Unpinning is Impeded by Filament Alignment with External Field”, Int J Sci Bas App Res 7, pp.355-361 (2014).
[pdf]
C.W. Zemlin and A.M. Pertsov .
"Anchoring of drifting spiral and scroll waves in excitable media", Phys Rev Lett 109, 038303 (2012).
[pdf]
M. Wellner, C.W. Zemlin and A.M. Pertsov
"Frustrated drift of an anchored scroll wave and the geodesic principle", Phys Rev E 82, 036122 (2010).
[pdf]
B. Caldwell, B. Mitrea, A.M.Pertsov, and C.W. Zemlin
"Probing field-induced tissue polarization using fluorescent imaging", Biophys J 99, pp. 2056-88 (2010).
[pdf]
X. Lin, J. Gemel, A. Glass, C.W. Zemlin, S. M. Taffet, E. C. Beyer, and R. Veenstra
"Connexin40 and Connexin43 Determine Gating Properties of Atrial Gap Junction Channels", J Mol Cell Cardiol 48, pp. 238-245 (2010).
[pdf]
C. W. Zemlin, B. G. Mitrea, and A. M. Pertsov
"Spontaneous onset of atrial fibrillation", Physica D 238, pp. 969-975 (2009)
[pdf]
C.J. Hyatt, C.W. Zemlin, R. M. Smith, A. M. Matiukas, A. M. Pertsov, and O. Bernus
" Reconstructing subsurface electrical wave orientation from cardiac epi-\ADfluorescence recordings: Monte Carlo versus diffusion approximation", Opt Express 16, pp. 13758-13772 (2008).
[pdf]
X. Lin, C. W. Zemlin, J. Hennan, J. Petersen, and R. Veenstra
"Rotigaptide Reduces the Inactivation of Ventricular Gap Junctions", Cardiovasc Res 79, pp. 416-426 (2008)
[pdf]
C. W. Zemlin, O. Bernus, A. Matiukas, and A. M. Pertsov
"Extracting Intramural Wavefront Orientation From Optical Upstroke Shapes in Whole Hearts", Biophys J 95, pp.942-50 (2008).
[pdf]
R. Smith, A. M. Matiukas, C. W. Zemlin, and A. M. Pertsov.
"Nondestructive Optical Determination of Fiber Organization in Whole Heart", Microsc Res Tech 71, pp. 510-16 (2008).
[pdf]
C.W. Zemlin and A.M. Pertsov
"Bradycardic onset of spiral wave re-entry: structural substrates." Europace, 9, pp. vi59-63 (2007). [pdf]
A. M. Pertsov, C. W. Zemlin, C. J. Hyatt, and O. Bernus
"What can we learn from the optically recorded epicardial action potential?" Biophys J, 91, pp. 3959-60 (2006). [pdf]
C. W. Zemlin, K. Mukund, V. Biktashev, and A. M. Pertsov
"Dynamics of Bound States of Same-Chirality Spiral Waves." Phys Rev E 74, 016207 (2006). [pdf]
C. W. Zemlin, S. F. Mironov, and A. M. Pertsov
"Near-threshold Field Stimulation: Intramural Versus Surface Activation." Cardiovasc Res 69, pp. 98-106 (2006). [pdf]
C. W. Zemlin, K. Mukund, M. Wellner, R. Zaritski, and A. M. Pertsov
"Asymmetric Bound States of Spiral Pairs in Excitable Media." Phys Rev Lett 95, 098302 (2005) [pdf]
C. J. Hyatt, S. F. Mironov, F. J. Vetter, C. W. Zemlin, and A. M. Pertsov
""Optical action potential upstroke morphology reveals near-surface transmural propagation direction." Circ Res 97, pp. 277-84 (2005). [pdf]
O. Bernus, C. W. Zemlin, R. Zaritski, S. F. Mironov, and A. M. Pertsov
"Alternating conduction in the ischemic border zone as a precursor of reentrant arrhythmias: a simulation study." Europace 7, Suppl. 2, pp. 93-104 (2005). [pdf]
C. W. Zemlin, S. Mironov, and A. Pertsov
"Delayed success in termination of three-dimensional reentry: role of surface polarization." J Cardiovasc Electrophysiol, 14, pp. S257-S263 (2003). [pdf]
A. V. Panfilov and C.W. Zemlin
"Wave propagation in an excitable medium with a negatively sloped restitution curve." Chaos 12, pp. 800-807, (2002). [pdf]
O. Bernus, R. Wilders, C. Zemlin, H. Verschelde, and A.V. Panfilov
"An efficient electrophysiological model of human ventricular cells." Am J Physiol 282, pp. H2296-2308, (2002). [pdf]
C. W. Zemlin, E. Storch, and H. Herzel
"Alternans and 2:1 rhythms in an ionic model of heart cells."Biosystems 66, pp. 1-10, (2002). [pdf]
C. W. Zemlin and A.V. Panfilov
"Spiral waves in excitable media with negative restitution." Phys Rev E 63, p. 041912 (2001). [pdf]
Abstracts (selected)
C. Zemlin and F. Xie
"Fast and Precise Ablation with Nanosecond Pulsed Electric Fields." Heart Rhythm, San Francisco (2014).
C. Zemlin, F. Xie, and S. Xiao
"Optimal parameters for the Ablation of Myocardial Tissue with Pulsed Electric Fields.", AHA Scientific Sessions, Dallas (2013).
F. Xie, S. Xiao, and C. Zemlin
"Treating Cardiac Arrhythmias with Nanosecond Pulsed Electric Fields." Bioelectrics, Karlsruhe, Germany (2013).
C. Zemlin and A. Pertsov
"Limits of the geodesic principle for scroll wave filaments." SIAM Conference, Snowbird, Utah (2013).
B. Hargrave, F. Li, F. Varghese, and C. Zemlin
"APlatelet gel activated with nanosecond pulsed electric fields promotes recovery from ischemia and restores electrical activity", Heart Rhythm, Denver (2013).
C. Zemlin, F. Varghese, F. Xie, and S.Xiao
"Ablation of Myocardial Tissue with Nanosecond Pulsed Electric Fields." Heart Rhythm, Denver (2013).
Book Chapters
C. W. Zemlin, H. Herzel, S.Y. Ho, and A.V. Panfilov.
"A realistic and efficient model of excitation propagation in the human atria." In N. Virag, O. Blanc, and L. Kappenberger, editors, Computer Simulation and Experimental Assessment of Cardiac Electrophysiology, pages 29-34, 2000.
Editorials
S. Deutsch, M. R. Urbano and C. Zemlin.
"Mouse models have limitations for development of medications for autism spectrum disorders, but also show much promise", Future Neurology 7 (1) , pp. 1-4 (2012). [pdf]
C. W. Zemlin and R. Veenstra.
"What is the structural substrate for atrial fibrillation?", Cardiology 114, pp. 19-21 (2009). [pdf]
2016
2015
2014 and earlier (selected)
C.W. Zemlin and A.M. Pertsov
"Bradycardic onset of spiral wave re-entry: structural substrates." Europace, 9, pp. vi59-63 (2007). [pdf]
A. M. Pertsov, C. W. Zemlin, C. J. Hyatt, and O. Bernus
"What can we learn from the optically recorded epicardial action potential?" Biophys J, 91, pp. 3959-60 (2006). [pdf]
C. W. Zemlin, K. Mukund, V. Biktashev, and A. M. Pertsov
"Dynamics of Bound States of Same-Chirality Spiral Waves." Phys Rev E 74, 016207 (2006). [pdf]
C. W. Zemlin, S. F. Mironov, and A. M. Pertsov
"Near-threshold Field Stimulation: Intramural Versus Surface Activation." Cardiovasc Res 69, pp. 98-106 (2006). [pdf]
C. W. Zemlin, K. Mukund, M. Wellner, R. Zaritski, and A. M. Pertsov
"Asymmetric Bound States of Spiral Pairs in Excitable Media." Phys Rev Lett 95, 098302 (2005) [pdf]
C. J. Hyatt, S. F. Mironov, F. J. Vetter, C. W. Zemlin, and A. M. Pertsov
""Optical action potential upstroke morphology reveals near-surface transmural propagation direction." Circ Res 97, pp. 277-84 (2005). [pdf]
O. Bernus, C. W. Zemlin, R. Zaritski, S. F. Mironov, and A. M. Pertsov
"Alternating conduction in the ischemic border zone as a precursor of reentrant arrhythmias: a simulation study." Europace 7, Suppl. 2, pp. 93-104 (2005). [pdf]
C. W. Zemlin, S. Mironov, and A. Pertsov
"Delayed success in termination of three-dimensional reentry: role of surface polarization." J Cardiovasc Electrophysiol, 14, pp. S257-S263 (2003). [pdf]
A. V. Panfilov and C.W. Zemlin
"Wave propagation in an excitable medium with a negatively sloped restitution curve." Chaos 12, pp. 800-807, (2002). [pdf]
O. Bernus, R. Wilders, C. Zemlin, H. Verschelde, and A.V. Panfilov
"An efficient electrophysiological model of human ventricular cells." Am J Physiol 282, pp. H2296-2308, (2002). [pdf]
C. W. Zemlin, E. Storch, and H. Herzel
"Alternans and 2:1 rhythms in an ionic model of heart cells."Biosystems 66, pp. 1-10, (2002). [pdf]
C. W. Zemlin and A.V. Panfilov
"Spiral waves in excitable media with negative restitution." Phys Rev E 63, p. 041912 (2001). [pdf]
Abstracts (selected)
C. Zemlin and F. Xie
"Fast and Precise Ablation with Nanosecond Pulsed Electric Fields." Heart Rhythm, San Francisco (2014).
C. Zemlin, F. Xie, and S. Xiao
"Optimal parameters for the Ablation of Myocardial Tissue with Pulsed Electric Fields.", AHA Scientific Sessions, Dallas (2013).
F. Xie, S. Xiao, and C. Zemlin
"Treating Cardiac Arrhythmias with Nanosecond Pulsed Electric Fields." Bioelectrics, Karlsruhe, Germany (2013).
C. Zemlin and A. Pertsov
"Limits of the geodesic principle for scroll wave filaments." SIAM Conference, Snowbird, Utah (2013).
B. Hargrave, F. Li, F. Varghese, and C. Zemlin
"APlatelet gel activated with nanosecond pulsed electric fields promotes recovery from ischemia and restores electrical activity", Heart Rhythm, Denver (2013).
C. Zemlin, F. Varghese, F. Xie, and S.Xiao
"Ablation of Myocardial Tissue with Nanosecond Pulsed Electric Fields." Heart Rhythm, Denver (2013).
Book Chapters
C. W. Zemlin, H. Herzel, S.Y. Ho, and A.V. Panfilov.
"A realistic and efficient model of excitation propagation in the human atria." In N. Virag, O. Blanc, and L. Kappenberger, editors, Computer Simulation and Experimental Assessment of Cardiac Electrophysiology, pages 29-34, 2000.
Editorials