Edelblute, C.E., Pakhomova, O.N, Li, F. Hargrave, B.Y., Heller, L.C. Donor platelet plasma components inactivate sensitive and multidrug resistant Acinetobacter baumannii isolates. Pathog Dis, 73(9). pii: ftv095, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26500225
Edelblute, C.E., Heller, L.C., Malik, M.A., Heller, R. Activated air produced by shielded sliding discharge plasma mediates plasmid DNA delivery to mammalian cells. Biotechnol Bioeng, 112:2583-2590, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26041378
Bosnjak, M., Dolinsek, T., Cemazar, M., Kranjc, S., Blagus, T., Markelc, B., Stimac, M., Kamensek, U., Heller, L., Bouquet, C., Sersa, G. Gene electrotransfer of Plasmid AMEP, an integrin targeted therapy, has antitumor and antiangiogenic action in murine B16 melanoma. Bosnjak, M., Dolinsek, T., Cemazar, M., Kranjc, S., Blagus, T., Markelc, B., Stimac, M., Kamensek, U., Heller, L., Bouquet, C., Sersa, G., Gene Ther, 22:578-590, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25781650
Edelblute CM, Malik MA, Heller LC. Surface-dependent inactivation of model microorganisms with shielded sliding atmospheric plasma discharges and applied air flow, Bioelectrochemistry 103:22-27, 2015.http://www.ncbi.nlm.nih.gov/pubmed/25200988.
Hao XM, A.M.; Edelblute, C.E.; Malik, M.A.; Heller, L.C.; Kolb, J.K. Nitric oxide generation with an air-operated non-thermal plasma jet and associated microbial inactivation mechanisms, Plasma Processes and Polymers 11:1044-1056, 2014.
http://onlinelibrary.wiley.com/doi/10.1002/ppap.201300187/pdf.
Edelblute CM, Donate AL, Hargrave BY, Heller LC. Human platelet gel supernatant inactivates opportunistic wound pathogens on skin, Platelets 26(1):13-6, 2015. http://www.ncbi.nlm.nih.gov/pubmed/24433255.
Heller L, Todorovic V, Cemazar M. Electrotransfer of single-stranded or double-stranded DNA induces complete regression of palpable B16.F10 mouse melanomas. Cancer Gene Ther. 2013;20(12):695-700. http://www.ncbi.nlm.nih.gov/pubmed/24287723.
Kolb JF, Mattson AM, Edelblute CM, Hao XL, Malik MA, Heller LC. Cold DC-Operated Air Plasma Jet for the Inactivation of Infectious Microorganisms. IEEE Trans Plasma Sci. 2012;40(11):3007-26. http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6316183.
Heller LC, Edelblute CM, Mattson AM, Hao X, Kolb JF. Inactivation of bacterial opportunistic skin pathogens by nonthermal DC-operated afterglow atmospheric plasma. Lett Appl Microbiol. 2012;54(2):126-32. http://www.ncbi.nlm.nih.gov/pubmed/22122358.
Gilbert R, Llewellyn JA, Schoenbach KH, Heller L, Hoff A. Exploring Tissue Response to Field Mediated Plasmid Delivery. ECS Transactions. 2011;35(7):145-55. http://link.aip.org/link/abstract/ECSTF8/v35/i7/p145/s1.
Guo S, Donate A, Basu G, Lundberg C, Heller L, Heller R. Electro-gene transfer to skin using a noninvasive multielectrode array. Journal of controlled release. 2011;151(3):256-62. http://www.ncbi.nlm.nih.gov/pubmed/21262290.
Ferraro B, Heller LC, Cruz YL, Guo S, Donate A, Heller R. Evaluation of delivery conditions for cutaneous plasmid electrotransfer using a multielectrode array. Gene Therapy. 2011;18(5):496-500. http://www.ncbi.nlm.nih.gov/pubmed/21179175.
Heller LC, Cruz YL, Ferraro B, Yang H, Heller R. Plasmid injection and application of electric pulses alter endogenous mRNA and protein expression in B16.F10 mouse melanomas. Cancer Gene Therapy. 2010;17(12):864-71. http://www.ncbi.nlm.nih.gov/pubmed/20706286.
Heller LC, Heller R. Electroporation gene therapy preclinical and clinical trials for melanoma. Curr Gene Ther. 2010;10(4):312-7. http://www.ncbi.nlm.nih.gov/pubmed/20557286.
Marshall WG, Jr., Boone BA, Burgos JD, Gografe SI, Baldwin MK, Danielson ML, et al. Electroporation-mediated delivery of a naked DNA plasmid expressing VEGF to the porcine heart enhances protein expression. Gene Ther. 2010;17(3):419-23. http://www.ncbi.nlm.nih.gov/pubmed/19956270.
Heller R, Cruz Y, Heller LC, Gilbert RA, Jaroszeski MJ. Electrically mediated delivery of plasmid DNA to the skin, using a multielectrode array. Hum Gene Ther. 2010;21(3):357-62. http://www.ncbi.nlm.nih.gov/pubmed/19839722.
Keeling WB, Myers AR, Stone PA, Heller L, Widen R, Back MR, et al. Regional antibiotic delivery for the treatment of experimental prosthetic graft infections. J Surg Res. 2009;157(2):223-6. http://www.ncbi.nlm.nih.gov/pubmed/19560786.
Heller LC, Jaroszeski MJ, Coppola D, Heller R. Comparison of electrically mediated and liposome-complexed plasmid DNA delivery to the skin. Genet Vaccines Ther. 2008;6(1):16-23. http://www.ncbi.nlm.nih.gov/pubmed/19055808.
Heller LC, Jones M, Widen RH. Comparison of DNA pyrosequencing with alternative methods for identification of mycobacteria. J Clin Microbiol. 2008;46(6):2092-4. http://www.ncbi.nlm.nih.gov/pubmed/18417659.
Peak KK, Duncan KE, Veguilla W, Luna VA, King DS, Heller L, et al. Bacillus acidiceler sp. nov., isolated from a forensic specimen, containing Bacillus anthracis pX02 genes. Int J Syst Evol Microbiol. 2007;57(Pt 9):2031-6. http://www.ncbi.nlm.nih.gov/pubmed/17766868.
Moroney SM, Heller LC, Arbuckle J, Talavera M, Widen RH. Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clones. J Clin Microbiol. 2007;45(3):1019-21. http://www.ncbi.nlm.nih.gov/pubmed/17192420.
Heller LC, Jaroszeski MJ, Coppola D, McCray AN, Hickey J, Heller R. Optimization of cutaneous electrically mediated plasmid DNA delivery using novel electrode. Gene Ther. 2007;14(3):275-80. http://www.ncbi.nlm.nih.gov/pubmed/16988718.
Hickey JD, Heller L, Heller R, Gilbert R. Electric field mediated DNA motion model. Bioelectrochemistry. 2007;70(1):101-3. http://www.ncbi.nlm.nih.gov/pubmed/16714149.
Heller LC, Heller R. In vivo electroporation for gene therapy. HumGene Ther. 2006;17(9):890-7. http://www.ncbi.nlm.nih.gov/pubmed/16972757.
Luna VA, King DS, Peak KK, Reeves F, Heberlein-Larson L, Veguilla W, et al. Bacillus anthracis virulent plasmid pX02 genes found in large plasmids of two other Bacillus species. J Clin Microbiol. 2006;44(7):2367-77. http://www.ncbi.nlm.nih.gov/pubmed/16825351.
Heller L, Merkler K, Westover J, Cruz Y, Coppola D, Benson K, et al. Evaluation of toxicity following electrically mediated interleukin-12 gene delivery in a B16 mouse melanoma model. Clin Cancer Res. 2006;12(10):3177-83. http://www.ncbi.nlm.nih.gov/pubmed/16707618.
Moroney SM, Heller LC, Widen RH. Evaluation of two TaqMan PCR assays for the detection of HIV-1 proviral DNA in blood samples. J Microbiol Methods. 2006;65(2):350-3. http://www.ncbi.nlm.nih.gov/pubmed/16169104.
Heller LC, Ugen K, Heller R. Electroporation for targeted gene transfer. Exp Op Drug Del. 2005;2(2):255-68. http://www.ncbi.nlm.nih.gov/pubmed/16296752
Davis CR, Heller LC, Peak KK, Wingfield DL, Goldstein-Hart CL, Bodager DW, et al. Real-time PCR detection of the thermostable direct hemolysin and thermolabile hemolysin genes in a Vibrio parahaemolyticus cultured from mussels and mussel homogenate associated with a foodborne outbreak. J Food Prot. 2004;67(5):1005-8. http://www.ncbi.nlm.nih.gov/pubmed/15151240.
Heller LC, Davis CR, Peak KK, Wingfield D, Cannons AC, Amuso PT, et al. Comparison of methods for DNA isolation from food samples for detection of Shiga toxin-producing Escherichia coli by real-time PCR. Appl Environ Microbiol. 2003;69(3):1844-6. http://www.ncbi.nlm.nih.gov/pubmed/12620880.
Gilbert R, Jaroszeski MJ, Heller L, Heller R. Electric field enhanced plasmid delivery to liver hepatocellular carcinomas. Technol Cancer Res Treat. 2002;1(5):355-64. http://www.ncbi.nlm.nih.gov/pubmed/12625761.
Lucas ML, Heller L, Coppola D, Heller R. IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma. Mol Ther. 2002;5(6):668-75. http://www.ncbi.nlm.nih.gov/pubmed/12027550.
Heller LC, Ingram SF, Lucas ML, Gilbert RA, Heller R. Effect of electrically mediated intratumor and intramuscular delivery of a plasmid encoding IFN alpha on visible B16 mouse melanomas. Technol Cancer Res Treat. 2002;1(3):205-9. http://www.ncbi.nlm.nih.gov/pubmed/12622513.
Heller L, Coppola D. Electrically mediated delivery of vector plasmid DNA elicits an antitumor effect. Gene Ther. 2002;9(19):1321-5. http://www.ncbi.nlm.nih.gov/pubmed/12224015.
Heller R, Schultz J, Lucas ML, Jaroszeski MJ, Heller LC, Gilbert RA, et al. Intradermal delivery of interleukin-12 plasmid DNA by in vivo electroporation. DNA Cell Biol. 2001;20(6):381-. http://www.ncbi.nlm.nih.gov/pubmed/11242540.
Heller L, Lucas ML. Delivery of plasmid DNA by in vivo electroporation. Gene Ther and Mol Biol. 2000. http://gtmb.org/volumes/Vol5/06%20%20Heller%20&%20Lucas,%2055-60.pdf.
Heller L, Pottinger C, Jaroszeski MJ, Gilbert R, Heller R. In vivo electroporation of plasmids encoding GM-CSF or interleukin-2 into existing B16 melanomas combined with electrochemotherapy induces longterm antitumour immunity. Melanoma Res. 2000;10(6):577-83. http://www.ncbi.nlm.nih.gov/pubmed/11198480.
Heller L, Jaroszeski MJ, Coppola D, Pottinger C, Gilbert R, Heller R. Electrically mediated plasmid DNA delivery to hepatocellular carcinomas in vivo. Gene Therapy. 2000;7(10):826-9. http://www.ncbi.nlm.nih.gov/pubmed/10845719.
Heller LC, Li Y, Abrams KL, Rogers MB. Transcriptional regulation of the Bmp2 gene. Retinoic acid induction in F9 embryonal carcinoma cells and Saccharomyces cerevisiae. J Biol Chem. 1999;274(3):1394-400. http://www.ncbi.nlm.nih.gov/pubmed/9880512.
Rogers MB, Glozak MA, Heller LC. Induction of altered gene expression in early embryos. Mutat Res. 1997;396(1-2):79-95. http://www.ncbi.nlm.nih.gov/pubmed/9434861.
Heller L, Orlean P, Adair WL, Jr. Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity. Proc Natl Acad Sci U S A. 1992;89(15):7013-6. http://www.ncbi.nlm.nih.gov/pubmed/1323123.